Neem tree extract has potential to treat pancreatic cancer

【11】Nature sub-journal: Neem tree extract has potential to treat pancreatic cancer

doi:10.1038/srep19819

A natural extract from the neem tree could potentially be used to treat pancreatic cancer, according to a new study. Relevant research results were recently published in the journal Scientific Reports. The paper is titled "Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition."

In the study, biomedical researchers from Texas Tech University Health Sciences Center at El Paso tested whether nimbolide, found in neem leaves, works in human pancreatic cancer cell lines and mice. Has anti-pancreatic cancer properties. Test results revealed that azadirachtone can not only prevent the growth and metastasis of pancreatic cancer, but also does not harm normal healthy cells.

Dr. Rajkumar Lakshmanaswamy, associate professor at Texas Tech University Health Sciences Center in El Paso, said, "Azadirachtone holds great promise, and the specificity of this treatment for cancer cells compared to normal cells is very attractive."

Pancreatic cancer has the highest mortality rate of all cancers: 94% of patients die within 5 years of diagnosis. This cancer grows rapidly and there is currently no effective treatment, underscoring the importance of developing new treatments.